Tyrosol ameliorates lipopolysaccharide-induced ocular inflammation in rats via inhibition of nuclear factor (NF)-κB activation
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Tyrosol ameliorates lipopolysaccharide-induced ocular inflammation in rats via inhibition of nuclear factor (NF)-κB activation
We evaluated the anti-inflammatory effect of tyrosol (Tyr) on endotoxin-induced uveitis (EIU) in rats. EIU was induced in male Lewis rats by subcutaneous injection of lipopolysaccharide (LPS). Tyr (10, 50 or 100 mg/kg) was intravenously injected 2 hr before, simultaneously and 2 hr after LPS injection. The aqueous humor (AqH) was collected 24 hr after LPS injection; the infiltrating cell number...
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3 4 Authors: Steven K. Malin1,2, John P. Kirwan1,2, Chang Ling Sia3, and Frank González3 5 6 7 1Dept. of Pathobiology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH; 8 2Dept. of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, OH; 9 3Dept. of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN. 10 11 12 13 14 Funding: Nationa...
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ژورنال
عنوان ژورنال: Journal of Veterinary Medical Science
سال: 2016
ISSN: 0916-7250,1347-7439
DOI: 10.1292/jvms.16-0166